Monkeypox Outbreak Poses ‘Real Risk’ To Public Health, WHO Official Says

The World Health Organization’s top official in Europe on Wednesday called for urgent action by the authorities and civic groups to control fast-rising cases of monkeypox that he said posed a real risk to public health. From a report: Europe has emerged as the epicenter of an outbreak of monkeypox, with more than 1,500 cases identified in 25 European countries, which account for 85 percent of global cases, the official, Dr. Hans Kluge, the W.H.O.’s director of its European region, said at a news conference. The W.H.O. will convene its emergency committee in Geneva next week, Dr. Kluge added, to determine if the outbreak constitutes a public health emergency of international concern, a formal declaration that calls for a coordinated response between countries.

“The magnitude of this outbreak poses a real risk,” Dr. Kluge said. “The longer the virus circulates, the more it will extend its reach, and the stronger the disease’s foothold will get in nonendemic countries.” Monkeypox is a viral infection endemic in West Africa, but it has now spread to 39 countries, including 32 that have no previous experience of it, the W.H.O. director, Dr. Tedros Adhanom Ghebreyesus, told reporters on Tuesday. Countries outside Africa and Europe that have identified cases of monkeypox include Australia, Brazil, Canada, Israel and the United States.

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Keychron’s Q3 Gives Mechanical Keyboard Fans Everything But the Numpad

An anonymous reader shares a review: In its early pre-pandemic days, Keychron made a name for itself with its series of affordable mechanical keyboards — including a few low-profile ones that remain a rarity to this day. Those boards didn’t necessarily appeal to enthusiasts, but were more than good enough for most mainstream users who wanted a different kind of keyboard. Last year, Keychron upped the ante with the launch of the Q1, an enthusiast-level, fully customizable hotswap keyboard with a 75% layout that had more than a few similarities to the heavily hyped GMMK Pro. Since then, Keychron has expanded this series with the 65% Q2, which received pretty rave reviews at the time and now the Q3.

The QMK-compatible Q3 clearly follows in the footsteps of the Q1 and Q2. It uses the same double-gasket design that should make for a relatively bouncy typing experience (though in my experience, there’s less bounce than I would’ve expected), and the overall design is pretty much the same, with the exception that it’s a tenkeyless (TKL), so you get a full keyboard with standalone arrow keys and a full row of function keys, but without the numpad. The body is made from aluminum and the whole unit weighs in at a hefty 4.5 pounds. In part, that’s because Keychron opted for a steel plate here. You can opt to get a bare-bones version where you supply your own switches and keycaps for $154 (or $164 if you want to get the optional volume knob), or a fully assembled version with keycaps and your choice of Gateron Pro Red, Blue or Brown switches for $174 (or $184 with knob). For the extra $20, I think getting the assembled version is a no-brainer, given that the keycaps and switches will cost you significantly more and even if you want to replace them, you could always reuse them in another project (because who only has one keyboard, right?).

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Crop Circles – and Why People Believed in Them

The New York Times tells the story of crop circles, “the mysterious patterns that regularly intrigued people around the world in the 1980s and ’90s, prompting speculation about alien visitors, ancient spiritual forces, weather anomalies, secret weapons tests and other theories.”

They call the phenomenon “a reminder that even before the era of social media and the internet, hoaxes were able to spread virally around the world and true believers could cling stubbornly to conspiracy theories despite a lack of evidence — or even the existence of evidence to the contrary.”

In the case of crop circles, the most important contradictory evidence emerged on Sept. 9, 1991, when the British newspaper Today ran a front-page story under the headline “Men who conned the world,” revealing that two mischievous friends from Southampton had secretly made more than 200 of the patterns over the previous decade.

Doug Bower, then 67, and his friend Dave Chorley, 62, admitted to a reporter, Graham Brough, that in the late 1970s they had begun using planks of wood with ropes attached to each end to stamp circles in crops by holding the ropes in their hands and pressing the planks underfoot. They had then watched with amusement as their anonymous antics eventually attracted media attention and began being copied by imitators around the world… The real-life pranksters phoned the newspaper to come clean, according to Mr. Brough, now 62, who says he verified their claims by checking an archive of more than 200 crop circle designs stored in a shed behind Mr. Bower’s home. The designs were clearly aged and matched the patterns they had made over the years, Mr. Brough said.

“I spent a week getting them to show me how they had done it all, and I have never laughed as much in my life,” he recalled. “The prevailing wisdom at the time was that aliens were about to land any day, but it had all been kicked off by these two blokes who’d have a couple of pints at their favorite pub and then head out into the night to have a bit of fun….”

“The people who wanted to keep believing in aliens and everything else just ignored the evidence, no matter how obvious it was,” said Rob Irving, who had begun emulating the two pranksters’ work in 1989 and befriended them after they went public…. “The power of the art came from the mystery, and Doug forever regretted coming forward because the mystery was lost.”

A professor of psychology at the University of Bristol in Britain explains to the Times the thought process of believers (which he says predated the internet). “instead of admitting that we live in a world we can’t control, they take comfort from believing that there is agency involved and someone who can be blamed.” The Times finds an example in a crop circle proponent who now believes, to this day, that even if crop circles are all man-made, the people making them have unwittingly “been prompted by an independent nonhuman mind.”

Although after a new crop circle appeared, the Times obtained an alternative perspective — from a neighboring farmer. “It is just so irresponsible to be trespassing and destroying food in the middle of a global wheat shortage.”

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Low-cost Astra Rocket Suffers Upper Stage Failure. Two NASA Satellites Lost

“All appeared to be going smoothly,” reports CBS News, “when, about a minute before the second stage engine was expected to shut down, an onboard ‘rocketcam’ showed a flash in the engine’s exhaust plume.

“The camera view them showed what appeared to be a tumble before video from the rocket cut off….”

California-based Astra on Sunday launched two shoebox-size NASA satellites from Cape Canaveral in a modest mission to improve hurricane forecasts, but the second stage of the company’s low-cost booster malfunctioned before reaching orbit and the payloads were lost.

“The upper stage shut down early and we did not deliver the payloads to orbit,” Astra tweeted. “We have shared our regrets with @NASA and the payload team. More information will be provided after we complete a full data analysis.”

It was the seventh launch of Astra’s small “Venture-class” rocket and the company’s fifth failure. Sunday’s launch was the first of three planned for NASA to launch six small CubeSats, two at a time, into three orbital planes. Given the somewhat risky nature of relying on tiny shoebox-size CubeSats and a rocket with a very short track record, the $40 million project requires just four satellites and two successful launches to meet mission objectives. The NASA contract calls for the final two flights by the end of July. Whether Astra can meet that schedule given Sunday’s failure is not yet known.

“Although today’s launch with @Astra did not go as planned, the mission offered a great opportunity for new science and launch capabilities,” tweeted NASA science chief Thomas Zurbuchen….
After Sunday’s failure, he tweeted: “Even though we are disappointed right now, we know: There is value in taking risks in our overall NASA Science portfolio because innovation is required for us to lead.”

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Two Tech CEOs Wanted Every Worker to Have a Permanent, Publicly-Available Job Performance File

“Two CEOs on a podcast casually proposed a shareable database of worker performance that would follow them between companies, forever, and encouraged listeners to create one,” writes Slashdot reader merauder128 , summarizing a recent article on Vice.

“HR professionals say it’s a terrible idea.”

Vice points out the podcast both the host and guest were CEOs of “data harvesters that package and resell data to other parties.”
Through one lens, it was a mundane musing between two CEOs of data companies talking about how awesome it would be to have more data on something. But in the context of experiments occurring in the tech industry around hiring practices, it was two influential CEOs encouraging other entrepreneurs to create a business that would be an absolute nightmare for workers, a type of credit score for workers that could be a permanent HR file that follows workers from one job to the next, and where a worker who struggles at one job may have trouble getting another….

It is also in line with a growing trend among tech companies that, spurred by work-from-home and hybrid work, are increasingly interested in quantifying employee performance. The most prominent example is Coinbase introducing an app so employees can constantly rate each other’s performances, a scenario even the normally cheery TechCrunch said “sounds rough.”
Over the last several years, there has been a boom in employee management software solutions such as Workday, Lattice, CultureAmp that are used across thousands of companies for performance reviews and other sensitive HR tasks. Technologically speaking, what Youakim and Hoffman are talking about is opening those confidential resources — or some condensed version of them that can be easily digested and analyzed — up to everyone.

None of these HR software companies have indicated that they have any intention of doing this.
The article warns that experts who have studied hiring extensively believe a permanent database database “would allow this complete, random mess to follow workers their entire careers, affecting their job prospects, earning potential, and their broader lives.” And the article summarizes a reaction to the idea from John Hausknecht, a professor of human resources at Cornell University. “It assumes people don’t change, that jobs require similar attributes, that a person’s experience at one company is relevant to another where they will be in a different environment with a different manager and different company culture….

“Or, to put it a different way, ‘Just because we can track it, collect it, and ask about it,’ Hausknecht said, ‘doesn’t necessarily mean we should.'”

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New CRISPR-based Map Ties Every Human Gene To Its Function

In 2003, the Human Genome Project finished sequencing every bit of human DNA, remembers MIT News.

“Now, over two decades later, MIT Professor Jonathan Weissman and colleagues have gone beyond the sequence to present the first comprehensive functional map of genes that are expressed in human cells.”
The data from this project, published online June 9 in Cell, ties each gene to its job in the cell, and is the culmination of years of collaboration on the single-cell sequencing method Perturb-seq.

The data are available for other scientists to use. “It’s a big resource in the way the human genome is a big resource, in that you can go in and do discovery-based research,” says Weissman, who is also a member of the Whitehead Institute and an investigator with the Howard Hughes Medical Institute….

“I think this dataset is going to enable all sorts of analyses that we haven’t even thought up yet by people who come from other parts of biology, and suddenly they just have this available to draw on,” says former Weissman Lab postdoc Tom Norman, a co-senior author of the paper.

The announcement credits the single-sequencing tool Perturb-seq and CRISPR-Cas9 genome editing which introduced genetic changes into cells and then captured information about which RNAs expressed (uses single-cell RNA sequencing).

The researchers scaled the method to the entire genome using human blood cancer cell lines and noncancerous cells derived from the retina, ultimately using Perturb-seq across more than 2.5 million cells.

Thanks to Slashdot reader Hmmmmmm for sharing the news.

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‘A Billion-Dollar Crypto Gaming Startup Promised Riches and Delivered Disaster’

“Even many Axie regulars say it’s not much fun, but that hasn’t stopped people from dedicating hours to researching strategies, haunting Axie-themed Discord channels and Reddit forums, and paying for specialized software that helps them build stronger teams…”

Bloomberg pays a visit to the NFT-based game Axie Infinity with a 39-year-old player who’s spent $40,000 there since last August — back when you could actually triple your money in a week. (“I was actually hoping that it could become my full-time job,” he says.)

The reason this is possible — or at least it seemed possible for a few weird months last year — is that Axie is tied to crypto markets. Players get a few Smooth Love Potion (SLP) tokens for each game they win and can earn another cryptocurrency, Axie Infinity Shards (AXS), in larger tournaments. The characters, themselves known as Axies, are nonfungible tokens, or NFTs, whose ownership is tracked on a blockchain, allowing them to be traded like a cryptocurrency as well….

Axie’s creator, a startup called Sky Mavis Inc., heralded all this as a new kind of economic phenomenon: the “play-to-earn” video game. “We believe in a world future where work and play become one,” it said in a mission statement on its website. “We believe in empowering our players and giving them economic opportunities. Welcome to our revolution.” By last October the company, founded in Ho Chi Minh City, Vietnam, four years ago by a group of Asian, European, and American entrepreneurs, had raised more than $160 million from investors including the venture capital firm Andreessen Horowitz and the crypto-focused firm Paradigm, at a peak valuation of about $3 billion. That same month, Axie Infinity crossed 2 million daily users, according to Sky Mavis.

If you think the entire internet should be rebuilt around the blockchain — the vision now referred to as web3 — Axie provided a useful example of what this looked like in practice. Alexis Ohanian, co-founder of Reddit and an Axie investor, predicted that 90% of the gaming market would be play-to-earn within five years. Gabby Dizon, head of crypto gaming startup Yield Guild Games, describes Axie as a way to create an “investor mindset” among new populations, who would go on to participate in the crypto economy in other ways. In a livestreamed discussion about play-to-earn gaming and crypto on March 2, former Democratic presidential contender Andrew Yang called web3 “an extraordinary opportunity to improve the human condition” and “the biggest weapon against poverty that we have.”

By the time Yang made his proclamations the Axie economy was deep in crisis. It had lost about 40% of its daily users, and SLP, which had traded as high as 40 cents, was at 1.8 cents, while AXS, which had once been worth $165, was at $56. To make matters worse, on March 23 hackers robbed Sky Mavis of what at the time was roughly $620 million in cryptocurrencies. Then in May the bottom fell out of the entire crypto market. AXS dropped below $20, and SLP settled in at just over half a penny. Instead of illustrating web3’s utopian potential, Axie looked like validation for crypto skeptics who believe web3 is a vision that investors and early adopters sell people to get them to pour money into sketchy financial instruments while hackers prey on everyone involved.

The article does credit the company for building its own blockchain (Ronin) to provide cheaper and faster NFT transactions. “Purists might have taken issue with the decision to abandon the core blockchain precept of decentralization, but on the other hand, the game actually worked.”

But the article also chronicles a fast succession of highs and lows:

“In Axie’s biggest market, the Philippines, the average daily earnings from May to October 2021 for all but the lowest-ranked players were above minimum wage, according to the gaming research and consulting firm Naavik.”

Axie raised $150 million to reimburse victims of the breach and repair its infrastructure. “But nearly two months later the systems compromised during the hack still weren’t up and running, and the executives were vague about when everything would be repaired. (A company spokesperson said on June 3 that this could happen by midmonth, pending the results of an external audit….): Days after the breach it launched Axie: Origin, a new alternate version with better graphics/gameplay — and without a cryptocurrency element. About 75% of the 39-year-old gamer’s co-players have “largely” stopped playing the game. “But at least one was sufficiently seduced by Axie’s potential to take a significant loan to buy AXS tokens, which he saw as a way to hedge against inflation of the Argentine peso. The local currency has indeed lost value since he took out the loan, but not nearly as much as AXS.”

Thanks to long-time Slashdot reader Parker Lewis for sharing the article

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Museum Restores 21 Rare Videos from Legendary 1976 Computing Conference

At Silicon Valley’s Computer History Museum, the senior curator just announced the results of a multi-year recovery and restoration process: making available 21 never-before-seen video recordings of a legendary 1976 conference:

For five summer days in 1976, the first generation of computer rock stars had its own Woodstock. Coming from around the world, dozens of computing’s top engineers, scientists, and software pioneers got together to reflect upon the first 25 years of their discipline in the warm, sunny (and perhaps a bit unsettling) climes of the Los Alamos National Laboratories, birthplace of the atomic bomb.

Among the speakers:

– A young Donald Knuth on the early history of programming languages

– FORTRAN designer John Backus on programming in America in the 1950s — some personal perspectives

– Harvard’s Richard Milton Bloch (who worked with Grace Hopper in 1944)

– Mathematician/nuclear physicist StanisÅaw M. Ulam on the interaction of mathematics and computing
– Edsger W. Dijkstra on “a programmer’s early memories.”

The Computer History Museum teases some highlights:

Typical of computers of this generation, the 1946 ENIAC, the earliest American large-scale electronic computer, had to be left powered up 24 hours a day to keep its 18,000 vacuum tubes healthy. Turning them on and off, like a light bulb, shortened their life dramatically. ENIAC co-inventor John Mauchly discusses this serious issue….
The Los Alamos peak moment was the brilliant lecture on the British WW II Colossus computing engines by computer scientist and historian of computing Brian Randell. Colossus machines were special-purpose computers used to decipher messages of the German High Command in WW II. Based in southern England at Bletchley Park, these giant codebreaking machines regularly provided life-saving intelligence to the allies. Their existence was a closely-held secret during the war and for decades after. Randell’s lecture was — excuse me — a bombshell, one which prompted an immediate re-assessment of the entire history of computing. Observes conference attendee (and inventor of ASCII) IBM’s Bob Bemer, “On stage came Prof. Brian Randell, asking if anyone had ever wondered what Alan Turing had done during World War II? From there he went on to tell the story of Colossus — that day at Los Alamos was close to the first time the British Official Secrets Act had permitted any disclosures. I have heard the expression many times about jaws dropping, but I had really never seen it happen before.”

Publishing these original primary sources for the first time is part of CHM’s mission to not only preserve computing history but to make it come alive. We hope you will enjoy seeing and hearing from these early pioneers of computing.

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